2001 Pilot Study Grants - Grants 1-26

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Funding from The Parkinson Alliance helped to finance the following Parkinson's research. Grantees were selected by scientific review committees of participating organizations. Abstracts and reports (when available) are available by clicking the underlined grants.

1. Alpha-synuclein Involvement in Transmitter Release--updated 3/2003
Ottavio Arancio, M.D., Ph.D.
The Nathan S. Kline Institute for Psychiatric Research, New York

2. Do Visual Attention and Imagery Deficits Affect Driving in Parkinsonism?--updated 3/2003
Anna M. Barrett, M.D.
Penn State College of Medicine, Pennsylvania

3. Genetic Modulation of Clinical Course in Pathologically Proven Parkinson's Disease--updated 3/2003
Richard Camicioli, M.D.
University of Alberta, Edmonton

4. Bone Marrow Stem Cell Delivery of GDNF in MPTP Mice--updated 3/2003
Lee Anna Cunningham, Ph.D.
University of New Mexico Health Science Center, New Mexico

5. Dopamine Receptor Dependent Subcellular Trafficking of NMDG Glutamate Receptors in Parkinson's Disease--updated 3/2003
Anthone W. Dunah, Ph.D.
The General Hospital Corporation, d/b/a/ Massachusetts General Hospital, Massachusetts

6. Role of Endogenous Cannibinoids in L-DOPA Dykinesias--updated 3/2003
Andrea Giuffrida, Ph.D.
University of California, Irvine, California

7. Role of Minocycline in the Inhibition of Microglial Activation and Protection of Dopaminergic Neurons in 6-OHDA Induced Parkinsonian Animal Model--updated 3/2003
Yi He, M.D. Ph.D.
Baylor College of Medicine, Texas

8. Neural Modulation of Working Memory by Levodopa in Parkinson's Disease
--updated 3/2003
Tamara Hershey, Ph.D.
Washington University, School of Medicine

9. The Effects of Tetrahydrobiopterin on Oxidative Stress and Mitochondrial Function--updated 3/2003
Un Jung Kang, M.D.
The University of Chicago, Illinois

10. Evaluation of a Large Cohort of Patients with Sporadic or Familial Parkinson's Disease for Involvement of the Parkin Gene -- updated 3/2003
Christine Klein, M.D.
Medical University of Luebeck, Germany

11. Do Mutations in the Alpha-synuclein Gene Cause Dopamine-dependent Oxidative Stress and Neurodegeneration in a Genetic Model of Parkinson's Disease?
Julie Lotharius, Ph.D.
Lund University, Sweden

12. Characterizing the Effects of Repetive Transcranial Magnetic Stimulation Frequency and Intensity on Cortical Excitability and Physical Fatigue in Patients with Parkinson's Disease--updated 3/2003
Jau-Shin Lou, M.D., Ph.D.
Oregon Health Sciences Unversity, Oregon

13. Conversion of Human Adult Bone Marrow Stem Cells into Dopamine Neurons
--updated 3/2003
Walter C. Low, Ph.D.
University of Minnesota, Minnesota

14. Mechanisms of Programmed Cell Death in a Model of Parkinson's Disease--updated 3/2003
Allen S. Mandir, M.D., Ph.D.
The Johns Hopkins University, School of Medicine, Maryland

15. Multiple Target Sites for Neural Transplantation in the Rat Model of Parkinson's Disease
--updated 3/2003
Ivar Mendez, M.D., Ph.D., FRCSC, FACS
Dalhousie University, Halifax, Nova Scotia

16. Role of CDK5 in an MPTP Model of Parkinson's Disease--updated 3/2003
David S. Park, Ph.D.
Ottawa Hospital Research Institute - NRI, Canada

17. Mitochondrial Aconitase Inactivation in MPTP Neurotoxicity--updated 3/2003
Manisha N. Patel, Ph.D.
National Jewish Medical and Research Center, Colorado

18. Structural and Functional Studies of the Parkin Ubiquitin Ligase -- updated 3/2003
Brenda A. Schulman, Ph.D.
St. Jude Children's Research Hospital, Tennessee

19. Functional Imaging of Speech in Parkinson's Disease
John J. Sidtis, Ph.D., L.P.
Diana Van Lancker, Ph.D., CCC/SLP
New York University, New York

20. Effect of STN Lesions and Stimulation Upon Striatal Neurotransmitter Release in PD Models--updated 3/2003
 Ruth Walker, M.D., Ph.D.
Bronx Veterans Research Foundation, New York

21. Neuronal Dopamine Transporter Associated Proteins (DTRAPs)--updated 3/2003
Katherine L. Widnell, M.D., Ph.D.
Johns Hopkins University School of Medicine, Maryland

22. Transplantation of Neural Stem Cells into a Rat Model of Parkinson's Disease
--updated 3/2003
Ming Yang, M.D., Ph.D.
Thomas Jefferson University Medical College, Philadelphia, Pennsylvania

23. An Approach to Integrate Transgenes into Desirable Locus for Inducible Expression in Dopamine Neurons--updated 3/2003
Xiaoxi Zhuang, Ph.D.
The University of Chicago, Illinois

24. Protein Dysfunction in Parkinsonism— Stimulation of Proteolysis as a Treatment for Parkinson’s Disease--updated 8/2002
Dr. Kevin McNaught
Harvard Medical School, Massachusetts

25. Physiological Restoration and In Vivo Neurochemistry--updated 8/2002
Dr. Aygul Balcioglu
Harvard Medical School, Massachusetts

26. Stem Cell Dopamine--updated 8/2000
Dr. Kwang-Soo Kim
Harvard Medical School, Massachusetts


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