Research Insights Archive

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November 1, 2014 – Parkinson’s disease patients with subthalamic stimulation and carers judge quality of life differently.

Lewis CJ, Maier F, Eggers C, Pelzer EA, Maarouf M, Moro E, Zurowski M, Kuhn J, Woopen C, Timmermann L. Parkinson’s disease patients with subthalamic stimulation and carers judge quality of life differently. , Parkinsonism Relat Disord. 2014 May;20(5):514-9. doi: 10.1016/j.parkreldis.2014.02.009. Epub 2014 Feb 20.Click here to read the abstract.


September 1, 2014 – STN vs. GPi Deep Brain Stimulation: Translating the Rematch into Clinical Practice

Williams NR, Foote KD, Okun MS. STN vs. GPi Deep Brain Stimulation: Translating the Rematch into Clinical Practice , 2014 Apr 1;1(1):24-35Click here to read the abstract.


July 1, 2014 – Predictive factors of speech intelligibility following subthalamic nucleus stimulation in consecutive patients with Parkinson

Tripoliti E1, Limousin P, Foltynie T, Candelario J, Aviles-Olmos I, Hariz MI, Zrinzo L. Predictive factors of speech intelligibility following subthalamic nucleus stimulation in consecutive patients with Parkinson , Mov Disord. 2014 Apr;29(4):532-8. doi: 10.1002/mds.25816. Epub 2014 Feb 14.Click here to read the abstract.


May 1, 2014 – The latest evidence on target selection in deep brain stimulation for Parkinson

Lukins TR, Tisch S, Jonker B. The latest evidence on target selection in deep brain stimulation for Parkinson , Neurosci. 2014 Jan; 21(1):22-7. doi: 10.1016/j.jocn.2013.05.011. Epub 2013 Nov 5.Click here to read the abstract.


April 1, 2014 – Importance of motor vs. non-motor symptoms for health-related quality of life in early Parkinson

Müller B1, Assmus J, Herlofson K, Larsen JP, Tysnes OB. Importance of motor vs. non-motor symptoms for health-related quality of life in early Parkinson , 2013 Nov;19(11):1027-32. doi: 10.1016/j.parkreldis.2013.07.010. Epub 2013 Aug Click here to read the abstract.


January 1, 2014 – Where are we with surgical therapies for Parkinson

Strauss I, Kalia SK, Lozano AM. Where are we with surgical therapies for Parkinson , 2014 Jan;20 Suppl 1:S187-91. doi: 10.1016/S1353-8020(13)70044-0.This article was a discussion of current surgical therapies for Parkinson’s disease (PD).  There are multiple treatments for PD and the typical primary therapy is the medicinal route (levodopa/carbidopa) which has shown to reduce common motor symptoms.  However, after long-term medication use there are known side effects (45% of people taking them for greater than 5 years will experience them) including dyskinesia, “wearing off,” and fluctuant levels during the day causing “on-off” periods.  Due to these challenges, surgical intervention is a secondary treatment option for people with PD (PWP).  The article noted that multiple studies have shown the efficacy of DBS and that approximately 100,000 PWP have undergone DBS over the past 20 years.  Even after 20 years though, there are still unanswered questions about this treatment, which the authors commented upon.Click here to read the abstract.


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