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September 24, 2019 – Impulse Control Disorders in Parkinson’s Disease: A 20-year Odyssey

Citation: Weintraub, D. (2019). Impulse control disorders in Parkinson’s disease: A 20‐year odyssey. Movement Disorders. Impulse Control Disorders (ICDs) are behavioral problems resulting from a person’s difficulty with or inability to resist the drive …


July 22, 2019 – Subthalamic Stimulation, Apomorphine, and Levodopa Infusion in Parkinson’s Disease

Citation: Dafsari, H. S., Martinez‐Martin, P., Rizos, A., Trost, M., dos Santos Ghilardi, M. G., Reddy, P., & Barbe, M. T. (2019). EuroInf 2: Subthalamic stimulation, apomorphine, and levodopa infusion in Parkinson’s disease. Movement Disorders, s3 …


May 22, 2019 – Clinical Management of Drug-Induced Dyskinesia in Parkinson’s Disease: Why Current Approaches May Need to Be Changed to Optimize Quality of Life

Citation: Daneault, J., Vergara-Diaz, G. & Lee, S. I. (2016). Clinical Management of Drug-Induced Dyskinesia in Parkinson’s Disease: Why Current Approaches May Need to Be Changed to Optimise Quality of Life. European Medical Journal, 1, 62-69. Intr …


March 22, 2019 – Profile of Inhaled Levodopa and its Potential in the Treatment of Parkinson’s Disease: Evidence to Date

Citation: Patel, A. B., & Jimenez-Shahed, J. (2018). Profile of inhaled levodopa and its potential in the treatment of Parkinson’s disease: evidence to date. Neuropsychiatric disease and treatment, 14, 2955. Introduction: Levodopa has been the gold …


January 21, 2019 – Predictors to Quality of life improvements after subthalamic stimulation in Parkinson’s Disease

Citation: Liu, F. T., Lang, L. Q., Yang, Y. J., Zhao, J., Feng, R., Hu, J., … & Wu, J. J. (2018). Predictors to quality‐of‐life improvements after subthalamic stimulation in Parkinson’s disease. Acta Neurologica Scandinavica.  Introduction: Subth …


November 8, 2018 – Parkinson Disease With and Without Dementia: A Prevalence Study and Future Projections

(Citation: Savica, R., Grossardt, B., Rocca, W., Bower, J. 2018. Parkinson disease with and without dementia: A prevalence study and future projections. Movement Disorders, 33 (4), 537-543)  Introduction: PD is the second most common neurodegenerative …


September 15, 2018 – Initial Cognitive Changes in Parkinson’s Disease

(Weintraub, D., Troster, A., Marras, C., & Stebbins, G. 2018. Initial cognitive changes in Parkinson’s disease. Movement Disorders, 33(4), 511-519) The latest research on cognition and Parkinson’s Disease has moved from focusing on individuals with …


July 23, 2018 – Cognitive Behavior Therapy for Anxiety in Parkinson’s disease: Outcomes for Patients and Caregivers

Dissanayaka, N., Pye, D., Mitchell, L., Byrne, G., O’Sullivan, J., Marsh, R., Pachana, N. 2017. Cognitive Behavior Therapy for Anxiety in Parkinson’s disease: Outcomes for Patients and Caregivers. Clinical Gerontol. 40(3), 159-171. More than 50% of ind …


May 16, 2018 – Falls in Parkinson’s Disease: A Complex and Evolving Picture

Fasano, A., Canning, C., Hausdorff, J., Lord, S., Rochester, L. 2017. Falls in Parkinson’s disease: A Complex and Evolving Picture. Movement Disorders, 32(11):1524-1536 Falls are a major determinant of reduced quality of life, reduced mobility, and red …


March 19, 2018 – Ocular and Visual Disorders in Parkinson’s Disease: Common but Frequently Overlooked

Journal of Neurology, Neurosurgery, and PsychiatryLittle S, Tripoliti E, Beudel M, Pogosyan A, Cagnan H, Herz D, Bestmann S, Aziz T, Cheeran B, Zrinzo L, Hariz M, Hyam J, Limousin P, Foltynie T, Brown P. Adaptive deep brain stimulation for Parkinson Journal of Neurology, Neurosurgery, and Psychiatry, 2016 Aug 16. pii: jnnp-2016-313518. doi: 10.1136/jnnp-2016-313518Click here to read the abstract.


May 1, 2017 – Adaptive deep brain stimulation for Parkinson

Journal of Neurology, Neurosurgery, and PsychiatryLittle S, Tripoliti E, Beudel M, Pogosyan A, Cagnan H, Herz D, Bestmann S, Aziz T, Cheeran B, Zrinzo L, Hariz M, Hyam J, Limousin P, Foltynie T, Brown P. Adaptive deep brain stimulation for Parkinson Journal of Neurology, Neurosurgery, and Psychiatry, 2016 Aug 16. pii: jnnp-2016-313518. doi: 10.1136/jnnp-2016-313518Click here to read the abstract.


April 1, 2017 – DBS means everything – for some time. Patients’ Perspectives on Daily Life with Deep Brain Stimulation for Parkinson’s Disease

Journal of Parkinson’s DiseaseHariz GM, Limousin P, Hamberg K.J DBS means everything – for some time. Patients’ Perspectives on Daily Life with Deep Brain Stimulation for Parkinson’s Disease Journal of Parkinson’s Disease, 2016 Mar 17;6(2):335-47. doi: 10.3233/JPD-160799Click here to read the abstract.


January 1, 2017 – Efficacies of globus pallidus stimulation and subthalamic nucleus stimulation for advanced Parkinson

Clinical interventions in agingTan ZG, Zhou Q, Huang T, Jiang Y. Clin Efficacies of globus pallidus stimulation and subthalamic nucleus stimulation for advanced Parkinson Clinical interventions in aging, 2016 Jun 21;11:777-86. doi: 10.2147/CIA.S105505. eCollection 2016.Parkinson’s disease (PD) is a common neurological condition that is initially treated with levodopa to control the motor symptoms.  The medications are frequently effective but as the disease progresses the medications are frequently not as effective and can cause adverse motor side effects (e.g. freezing and dyskinesias) for People with Parkinson’s disease (PWP).  Additional therapies were created, deep brain stimulation (DBS), in the 1990’s and have consistently shown efficacy in controlling motor symptoms for PWP.  Much of the earlier research focused on the motor control and did not pay as close attention to the nonmotor symptoms which can also be very disabling.  Recent research has focused on neurocognitive outcomes and these authors conducted a meta-analysis to review such studies.Click here to read the abstract.


November 1, 2016 – Increased body mass index associated with autonomic dysfunction in Parkinson

Parkinsonism & Related DisordersMochizuki H1, Taniguchi A2, Nakazato Y3, Ishii N4, Ebihara Y5, Sugiyama T6, Shiomi K7, Nakazato M8 Increased body mass index associated with autonomic dysfunction in Parkinson Parkinsonism & Related Disorders, 2016 Mar;24:129-31. doi: 10.1016/j.parkreldis.2016.01.007. Epub 2016 Jan 9Click here to read the abstract.


July 1, 2016 – DBS means everything – for some time. Patients

Parkinsonism & Related DisordersHariz GM, Limousin P, Hamberg K. DBS means everything – for some time. Patients Parkinsonism & Related Disorders, 2016 Mar 17.Click here to read the abstract.


May 1, 2016 – Computer-Guided Deep Brain Stimulation (DBS) Programming for Parkinson

NeuromodulationHeldman DA, Pulliam CL, Urrea Mendoza E, Gartner M, Giuffrida JP, Montgomery EB Jr, Espay AJ, Revilla FJ. Computer-Guided Deep Brain Stimulation (DBS) Programming for Parkinson Neuromodulation, 2016 Feb;19(2):127-32. doi: 10.1111/ner.12372. Epub 2015 Dec 1. PMID: 26621764Click here to read the abstract.


April 1, 2016 – Deep brain stimulation may reduce the relative risk of clinically important worsening in early stage Parkinson

Hacker ML, Tonascia J, Turchan M, Currie A, Heusinkveld L, Konrad PE, Davis TL, Neimat JS, Phibbs FT, Hedera P, Wang L, Shi Y, Shade DM, Sternberg AL, Drye LT, Charles D. Deep brain stimulation may reduce the relative risk of clinically important worsening in early stage Parkinson , 2015 Oct;21(10):1177-83. doi: 10.1016/j.parkreldis.2015.08.008. Epub 2015 Aug 11. PMID:Click here to read the abstract.


January 1, 2016 – Update on deep brain stimulation in Parkinson

Translational NeurodegenerationMartinez-Ramirez D, Hu W, Bona AR, Okun MS, Wagle Shukla A. Update on deep brain stimulation in Parkinson Translational Neurodegeneration, 2015 Jun 27;4:12. doi: 10.1186/s40035-015-0034-0. eCollection 2015. PMID: 26257895 Free PMC ArticleClick here to read the abstract.


November 1, 2015 – Advances in functional neurosurgery for Parkinson’s disease.

Movement DisordersMetman LV, Slavin KV. Advances in functional neurosurgery for Parkinson’s disease. Movement Disorders, 2015 Sep 15;30(11):1461-70. doi: 10.1002/mds.26338. Epub 2015 Aug 14Click here to read the abstract.


September 1, 2015 – Incidence and mortality trends of aspiration pneumonia in Parkinson, 1979-2010.

Akbar U, Dham B, He Y, Hack N, Wu S, Troche M, Tighe P, Nelson E, Friedman JH, Okun MS. Incidence and mortality trends of aspiration pneumonia in Parkinson, 1979-2010. , Parkinsonism Relat Disord. 2015 Sep; 21(9):1082-6. doi: 10.1016/j.parkreldis.2015.06.020. Epub 2015 Jul 2.Click here to read the abstract.


July 1, 2015 – The medical treatment of patients with Parkinson

Alexoudi A, Shalash A, Knudsen K, Witt K, Mehdorn M, Volkmann J, Deuschl G. The medical treatment of patients with Parkinson , 2015 Jun;21(6):555-60. doi: 10.1016/j.parkreldis.2015.03.003. Epub 2015 Mar 20Click here to read the abstract.


April 1, 2015 – Combining cell transplants or gene therapy with deep brain stimulation for Parkinson’s disease.

Movement DisordersRowland NC, Starr PA, Larson PS, Ostrem JL, Marks WJ Jr, Lim DA Combining cell transplants or gene therapy with deep brain stimulation for Parkinson’s disease. Movement Disorders, Mov Disord. 2014 Dec 17. doi: 10.1002/mds.26083.Click here to read the abstract.


January 1, 2015 – Effect of advancing age on outcomes of deep brain stimulation for Parkinson disease.

DeLong MR, Huang KT, Gallis J, Lokhnygina Y, Parente B, Hickey P, Turner DA, Lad SP. Effect of advancing age on outcomes of deep brain stimulation for Parkinson disease. , 2014 Oct;71(10):1290-5. doi: 10.1001/jamaneurol.2014.1272.Click here to read the abstract.


November 1, 2014 – Parkinson’s disease patients with subthalamic stimulation and carers judge quality of life differently.

Lewis CJ, Maier F, Eggers C, Pelzer EA, Maarouf M, Moro E, Zurowski M, Kuhn J, Woopen C, Timmermann L. Parkinson’s disease patients with subthalamic stimulation and carers judge quality of life differently. , Parkinsonism Relat Disord. 2014 May;20(5):514-9. doi: 10.1016/j.parkreldis.2014.02.009. Epub 2014 Feb 20.Click here to read the abstract.


September 1, 2014 – STN vs. GPi Deep Brain Stimulation: Translating the Rematch into Clinical Practice

Williams NR, Foote KD, Okun MS. STN vs. GPi Deep Brain Stimulation: Translating the Rematch into Clinical Practice , 2014 Apr 1;1(1):24-35Click here to read the abstract.


July 1, 2014 – Predictive factors of speech intelligibility following subthalamic nucleus stimulation in consecutive patients with Parkinson

Tripoliti E1, Limousin P, Foltynie T, Candelario J, Aviles-Olmos I, Hariz MI, Zrinzo L. Predictive factors of speech intelligibility following subthalamic nucleus stimulation in consecutive patients with Parkinson , Mov Disord. 2014 Apr;29(4):532-8. doi: 10.1002/mds.25816. Epub 2014 Feb 14.Click here to read the abstract.


May 1, 2014 – The latest evidence on target selection in deep brain stimulation for Parkinson

Lukins TR, Tisch S, Jonker B. The latest evidence on target selection in deep brain stimulation for Parkinson , Neurosci. 2014 Jan; 21(1):22-7. doi: 10.1016/j.jocn.2013.05.011. Epub 2013 Nov 5.Click here to read the abstract.


April 1, 2014 – Importance of motor vs. non-motor symptoms for health-related quality of life in early Parkinson

Müller B1, Assmus J, Herlofson K, Larsen JP, Tysnes OB. Importance of motor vs. non-motor symptoms for health-related quality of life in early Parkinson , 2013 Nov;19(11):1027-32. doi: 10.1016/j.parkreldis.2013.07.010. Epub 2013 Aug Click here to read the abstract.


January 1, 2014 – Where are we with surgical therapies for Parkinson

Strauss I, Kalia SK, Lozano AM. Where are we with surgical therapies for Parkinson , 2014 Jan;20 Suppl 1:S187-91. doi: 10.1016/S1353-8020(13)70044-0.This article was a discussion of current surgical therapies for Parkinson’s disease (PD).  There are multiple treatments for PD and the typical primary therapy is the medicinal route (levodopa/carbidopa) which has shown to reduce common motor symptoms.  However, after long-term medication use there are known side effects (45% of people taking them for greater than 5 years will experience them) including dyskinesia, “wearing off,” and fluctuant levels during the day causing “on-off” periods.  Due to these challenges, surgical intervention is a secondary treatment option for people with PD (PWP).  The article noted that multiple studies have shown the efficacy of DBS and that approximately 100,000 PWP have undergone DBS over the past 20 years.  Even after 20 years though, there are still unanswered questions about this treatment, which the authors commented upon.Click here to read the abstract.


November 1, 2013 – Deep brain stimulation improves survival in severe Parkinson

Ngoga D, Mitchell R, Kausar J, Hodson J, Harries A, Pall H. Deep brain stimulation improves survival in severe Parkinson , 2013 Jul 10Click here to read the abstract.


September 1, 2013 – Theoretical analysis of the local field potential in deep brain stimulation applications.

Lempka SF, McIntyre CC Theoretical analysis of the local field potential in deep brain stimulation applications. , PLoS One. 2013;8(3):e59839. doi: 10.1371/journal.pone.0059839. Epub 2013 Mar 28.Click here to read the abstract.


June 1, 2013 – Timing of deep brain stimulation in Parkinson

Desouza R, Moro E, Lang A, Schapira A. Ann Neurol. Timing of deep brain stimulation in Parkinson , 2013 Mar 8. doi: 10.1002/ana.23890. [Epub ahead of print]Click here to read the abstract.


April 1, 2013 – Effect of deep brain stimulation on speech performance in Parkinson’s disease.

EpubEffect of deep brain stimulation on speech performance in Parkinson’s disease. Effect of deep brain stimulation on speech performance in Parkinson’s disease. Epub, S. Parkinsons Dis. 2012;2012:850596. doi: 10.1155/2012/850596. Epub 2012 Nov 21.Click here to read the abstract.


February 1, 2013 – Amantadine improves gait in PD patients with STN stimulation.

Parkinsonism & Related DisordersChan H-F, Kukkle PL, Merello M, Lim SY, Poon YY, Moro E. Amantadine improves gait in PD patients with STN stimulation. Parkinsonism & Related Disorders, Parkinsonism and Related Disorders. 2012 Dec 6. pii: S1353-8020(12)00438-5. doi: 10.1016/j.parkreldis.2012.11.005.Click here to read the abstract.


January 1, 2013 – Effects of deep brain stimulation in the subthalamic nucleus or globus pallidus internus on step initiation in Parkinson disease.

Journal of NeurosurgeryRocchi L, Carlson-Kuhta P, Chiari L, Burchiel KJ, Hogarth P, Horak FB. Effects of deep brain stimulation in the subthalamic nucleus or globus pallidus internus on step initiation in Parkinson disease. Journal of Neurosurgery, 2012 Dec;117(6):1141-9. doi: 10.3171/2012.8.JNS112006. Epub 2012 Oct 5.Click here to read the abstract.


November 1, 2012 – Cognitive Rehabilitation for Executive Dysfunction in Parkinson’s Disease

Calleo, J., Burrows, C., Levin, H., Marsh, L., Lai, E., York, M. (2012) Cognitive Rehabilitation for Executive Dysfunction in Parkinson’s Disease , Parkinson’s Disease, vol. 2012, Article ID 512892, 6 pagesClick here to read the abstract.


September 1, 2012 – Randomized trial of deep brain stimulation for Parkinson disease: Thirty-six-month outcomes.

NeurologyWeaver FM, Follett KA, Stern M, Luo P, Harris CL, Hur K, Marks WJ Jr, Rothlind J, Sagher O, Moy C, Pahwa R, Burchiel K, Hogarth P, Lai EC, Duda JE, Holloway K, Samii A, Horn S, Bronstein JM, Stoner G, Starr PA, Simpson R, Baltuch G, De Salles A, Huang GD, Reda DJ; For the CSP 468 Study Group. Randomized trial of deep brain stimulation for Parkinson disease: Thirty-six-month outcomes. Neurology, 2012 Jul 3;79(1):55-65. Epub 2012 Jun 20.Click here to read the abstract.


July 1, 2012 – Controlling Gait Coordination with STN-DBS Improves Freezing of Gait in Parkinson’s disease

Fasano, A., Herzog, J., Seifert, E., Stolze, H., Falk, D., Reese, R., Volkmann, J., Deuschl, G. (2011). Controlling Gait Coordination with STN-DBS Improves Freezing of Gait in Parkinson’s disease , Modulation of gait coordination by subthalamic stimulation improves freezing of gait. Movement Disorders, 26(6): 844-851.Click here to read the abstract.


July 1, 2012 – Effects of subthalamic nucleus deep brain stimulation and L-dopa on blinking in Parkinson

Bologna M, Fasano A, Modugno N, Fabbrini G, Berardelli A. Effects of subthalamic nucleus deep brain stimulation and L-dopa on blinking in Parkinson , Exp Neurol. 2012 Feb 14. Doi: 10.1016/j.expneurol.2012.02.004Click here to read the abstract.


May 1, 2012 – Nonmotor outcomes in Parkinson’s disease: is deep brain stimulation better than dopamine replacement therapy?

Borgohain R, Kandadai RM, Jabeen A, Kannikannan MA. Nonmotor outcomes in Parkinson’s disease: is deep brain stimulation better than dopamine replacement therapy? , 2012 Jan;5(1):23-41Click here to read the abstract.


April 1, 2012 – Instability of syllable repetition in Parkinson’s disease—influence of levodopa and deep brain stimulation.

Skodda, S., Flasskamp, A., Schlegel, U. Instability of syllable repetition in Parkinson’s disease—influence of levodopa and deep brain stimulation. , 26(4): 728-730.Click here to read the abstract.


January 1, 2012 – Do stable patients with a premorbid depression history have a worse outcome after deep brain stimulation for Parkinson disease?

NeurosurgeryOkun MS, Wu SS, Foote KD, Bowers D, Gogna S, Price C, Malaty I, Rodriguez RL, Jacobson CE, Ward H. Do stable patients with a premorbid depression history have a worse outcome after deep brain stimulation for Parkinson disease? Neurosurgery, 2011 Aug;69(2):357-60; discussion 360-1.Click here to read the abstract.


November 1, 2011 – Perceived Changes in Communication as an Effect of STN Surgery in Parkinson’s Disease: A Qualitative Interview Study.

Ahlberg E, Laakso K, Hartelius L. Perceived Changes in Communication as an Effect of STN Surgery in Parkinson’s Disease: A Qualitative Interview Study. , Parkinsons Dis. 2011;2011:540158. Epub 2011 Aug 14. Click here to read the abstract.


September 1, 2011 – Laserlight cues for gait freezing in Parkinson’s disease: an open-label study.

Donovan, S., Lim, C., Diaz, N., Browner, N., Rose, P., Sudarsky, L.R., Tarsy, D., Fahn, S., Simon, D.K. Parkinsonism & Related Disorders, 17(4): 240-245. Laserlight cues for gait freezing in Parkinson’s disease: an open-label study. , Click here to read the abstract.


July 1, 2011 – DBS Therapy for Parkinson’s disease: Current-controlled DBS vs. Voltage-Controlled DBS

Lepmkal, S.F., Johnson, M.D., Miocinovic, S., Vitek, J.L., McIntyre, C.C. (2010) DBS Therapy for Parkinson’s disease: Current-controlled DBS vs. Voltage-Controlled DBS , 121(12): 2128-2133.Click here to read the abstract.


May 1, 2011 – Parkinson’s disease DBS: what, when, who and why? The time has come to tailor DBS targets.

Okun MS, Foote KD. Parkinson’s disease DBS: what, when, who and why? The time has come to tailor DBS targets. , Expert Rev Neurother. 2010 Dec; 10(12):1847-57Click here to read the abstract.


April 1, 2011 – Long-term effects of pallidal or subthalamic deep brain stimulation on quality of life in Parkinson’s disease.

Volkmann, J., Albanese, A., Kulisevsky, J., Tornqvist, A., Houeto, J., Pidoux, B., Bonnet, A., Mendes, A., Benabid, A., Fraix, V., Blercom, N.V., Xie, J., Obeso, J., Rodrigues-Oroz, M.C., Guridi, J., Schnitzler, A., Timmermann, L., Gironell, A., Molet, J., Pascual-Sedano, B., Rehncrona, S., Moro, E., Lang, A., Lozano, A.M., Bentivoglio, A.R., Scerrati, M., Contarino, M.F., Romito, L., Janssens, M., Agid, Y. (2009) Long-term effects of pallidal or subthalamic deep brain stimulation on quality of life in Parkinson’s disease. , 24(8): 1154-61Click here to read the abstract.


April 1, 2011 – Best surgical practices: a stepwise approach to the University of Pennsylvania deep brain stimulation protocol.

Kramer DR, Halpern CH, Buonacore DL, McGill KR, Hurtig HI, Jaggi JL, Baltuch GH. Best surgical practices: a stepwise approach to the University of Pennsylvania deep brain stimulation protocol. , Neurosurg Focus. 2010 Aug; 29(2): E3Click here to read the abstract.


January 1, 2011 – Effects of subthalamic stimulation on speech of consecutive patients with Parkinson disease.

Tripoliti E, Zrinzo L, Martinez-Torres I, Frost E, Pinto S, Foltynie T, Holl E, Petersen E, Roughton M, Hariz MI, Limousin P. Effects of subthalamic stimulation on speech of consecutive patients with Parkinson disease. , 2010 Nov 10Click here to read the abstract.


November 1, 2010 – Early versus delayed bilateral subthalamic deep brain stimulation for Parkinson’s disease: A decision analysis.

Espay AJ, Vaughan JE, Marras C, Fowler R, Eckman MH. Early versus delayed bilateral subthalamic deep brain stimulation for Parkinson’s disease: A decision analysis. , 2010 May 21. [Epub ahead of print]Click here to read the abstract.


November 1, 2010 – Patient-specific models of deep brain stimulation: Influence of field model complexity on neural activation predictions.

Chaturvedi A, Butson CR, Lempka SF, Cooper SE, McIntyre CC. Patient-specific models of deep brain stimulation: Influence of field model complexity on neural activation predictions. , Brain Stimul. 2010 Apr;3(2):65-77.Click here to read the abstract.


September 1, 2010 – A Longitudinal Program for Biomarker Development in Parkinson’s Disease: A Feasibility Study

Ravina, B., Tanner, C., DiEuliis, D., Eberly, S., Flagg, E., Galpern, W.R., Fahn, S., Goetz, C.G., Grate, S., Kurlan, R., Lang, A.E., Marek, K., Kieburtz, K., Oakes, D., Elliott, R., Shoulson, I., Parkinson Study Group LAPBS-PD Investigators. A Longitudinal Program for Biomarker Development in Parkinson’s Disease: A Feasibility Study , Movement Disorders, 24(14): 2081-90Click here to read the abstract.


September 1, 2010 – Standard guidelines for publication of deep brain stimulation studies in Parkinson’s disease

Vitek JL, Lyons KE, Bakay R, Benabid AL, Deuschl G, Hallett M, Kurlan R, Pancrazio JJ, Rezai A, Walter BL, Lang AE. Mov Disord. 2010 Jun 11. Standard guidelines for publication of deep brain stimulation studies in Parkinson’s disease , Click here to read the abstract.


July 1, 2010 – Complications of deep brain stimulation: a collective review.

Chan DT, Zhu XL, Yeung JH, Mok VC, Wong E, Lau C, Wong R, Lau C, Poon WS. Complications of deep brain stimulation: a collective review. , Asian Journal of Surgery 2009 Oct; 32(4):258-63.Click here to read the abstract.


May 1, 2010 – Customizing deep brain stimulation to the patient using computational models.

McIntyre CC, Frankenmolle AM, Wu J, Noecker AM, Alberts JL. Customizing deep brain stimulation to the patient using computational models. , Conf Proc IEEE Eng Med Biol Soc. 2009; 2009:4228-9.Click here to read the abstract.


April 1, 2010 – The number and nature of emergency department encounters in patients with deep brain stimulators.

Resnick AS, Foote KD, Rodriguez RL, Malaty IA, Moll JL, Carden DL, Krock NE, Medley MM, Burdick A, Haq IU, Okun MS. The number and nature of emergency department encounters in patients with deep brain stimulators. , 2010 Jan; 257(1):122-31Click here to read the abstract.


January 1, 2010 – Non-motor functions in parkinsonian patients implanted in the pedunculopontine nucleus: Focus on sleep and cognitive domains.

Stefani A, Roberto C, Livia B, Mariangela P, Alberto C, Salvatore G, Fabio P, Andrea R, Cesare I, Francesco M, Antonella P. (2009) Non-motor functions in parkinsonian patients implanted in the pedunculopontine nucleus: Focus on sleep and cognitive domains. , J Neurol Sci. 2009 Sep 16. [Epub ahead of print].Click here to read the abstract.


November 1, 2009 – Predictors of cognitive and psychosocial outcome after STN DBS in Parkinson Disease.

Smeding HM, Speelman JD, Huizenga HM, Schuurman PR, Schmand B. Predictors of cognitive and psychosocial outcome after STN DBS in Parkinson Disease. , 2009 May 21. [Epub ahead of print]Click here to read the abstract.


September 1, 2009 – Surgical repositioning of misplaced subthalamic electrodes in Parkinson’s disease: location of effective and ineffective leads.

Richardson RM, Ostrem JL, Starr PA Surgical repositioning of misplaced subthalamic electrodes in Parkinson’s disease: location of effective and ineffective leads. , 2009;87(5):297-303. Epub 2009 Jul 29Click here to read the abstract.


July 1, 2009 – Chronic subthalamic deep brain stimulation improves pain in Parkinson disease.

Kim HJ, Paek SH, Kim JY, Lee JY, Lim YH, Kim MR, Kim DG, Jeon BS. Chronic subthalamic deep brain stimulation improves pain in Parkinson disease. , Dec; 255(12):1889-94. Epub 2009 Jan 22Click here to read the abstract.


April 1, 2009 – Cognition and mood in Parkinson’s disease in subthalamic nucleus versus globus pallidus interna deep brain stimulation: The COMPARE Trial.

Okun MS, Fernandez HH, Wu SS, Kirsch-Darrow L, Bowers D, Bova F, Suelter M, Jacobson CE 4th, Wang X, Gordon CW Jr, Zeilman P, Romrell J, Martin P, Ward H, Rodriguez RL, Foote KD. Cognition and mood in Parkinson’s disease in subthalamic nucleus versus globus pallidus interna deep brain stimulation: The COMPARE Trial. , March 13, 2009Click here to read the abstract.


January 1, 2009 – Reoperation for suboptimal outcomes after deep brain stimulation surgery.

Ellis TM, Foote KD, Fernandez HH, Sudhyadhom A, Rodriguez RL, Zeilman P, Jacobson CE 4th, Okun MS. (2008). Reoperation for suboptimal outcomes after deep brain stimulation surgery. , Neurosurgery. 2008 Oct;63(4):754-60; discussion 760-1.Click here to read the abstract.


November 1, 2008 – Does deep brain stimulation induce apathy in Parkinson’s disease?

Kirsch-Darrow L, Mikos A, Bowers D. (2008) Does deep brain stimulation induce apathy in Parkinson’s disease? , 2008 May 1;13:5316-22Click here to read the abstract.


September 1, 2008 – Chronic pain in Parkinson’s disease: the cross-sectional French DoPaMiP survey.

Nègre-Pagès L, Regragui W, Bouhassira D, Grandjean H, Rascol O; DoPaMiP Study Group Chronic pain in Parkinson’s disease: the cross-sectional French DoPaMiP survey. , 2008 Jul 30; 23(10):1361-9Click here to read the abstract.


July 1, 2008 – Sleep and PWP

Mehta SH, Morgan JC, Sethi KD. (2008), Sleep disorders associated with Parkinson’s disease: role of dopamine, epidemiology, and clinical scales of assessment. Sleep and PWP , CNS Spectr. 2008 Mar;13 (3 Suppl 4):6-11.Click here to read the abstract.


May 1, 2008 – Surgical Treatment of PD

Moreau C, Defebvre L, Destée A, Bleuse S, Clement F, Blatt JL, Krystkowiak P, Devos D. (2008) Surgical Treatment of PD , STN-DBS frequency effects on freezing of gait in advanced Parkinson disease. Neurology. 2008 Apr 16 [Epub ahead of print]Click here to read the abstract.


May 1, 2008 – Management of motor complications in advanced Parkinson’s disease.

Melamed E, Ziv I, Djaldetti R. (2007) Management of motor complications in advanced Parkinson’s disease. , Mov Disord. 2007 Sep; 22 Suppl. 17:S379-84.Click here to read the abstract.


May 1, 2008 – Effects of subthalamic nucleus stimulation and levodopa on the autonomic nervous system in Parkinson’s disease.

Ludwig J, Remien P, Guballa C, Binder A, Binder S, Schattschneider J, Herzog J, Volkmann J, Deuschl G, Wasner G, Baron R. Effects of subthalamic nucleus stimulation and levodopa on the autonomic nervous system in Parkinson’s disease. , J Neurol Neurosurg Psychiatry. 2007 Jul;78(7):742-5. Epub 2007 Mar 19Click here to read the abstract.


April 1, 2008 – Deep brain stimulation hardware complications: The role of electrode impedance and current measurements.

Farris S, Vitek J, Giroux ML. (2008), Deep brain stimulation hardware complications: The role of electrode impedance and current measurements. , Mov Disord. 2008 Jan 9 [Epub ahead of print]Click here to read the abstract.


January 1, 2008 – Long-term outcome of 50 consecutive Parkinson’s disease patients treated with subthalamic deep brain stimulation.

Wider C, Pollo C, Bloch J, Burkhard PR, Vingerhoets FJ. (2007) Long-term outcome of 50 consecutive Parkinson’s disease patients treated with subthalamic deep brain stimulation. , Parkinsonism Relat Disord. 2007 Sep 5 [Epub ahead of print]Click here to read the abstract.


November 1, 2007 – Effects of subthalamic deep brain stimulation on dysarthrophonia in Parkinson’s disease.

Klostermann F, Ehlen F, Vesper J, Nubel K, Gross M, Marzinzik F, Curio G, Sappok T. (2007) Effects of subthalamic deep brain stimulation on dysarthrophonia in Parkinson’s disease. , J Neurol Neurosurg Psychiatry. 2007 Aug 31; [Epub ahead of print]Click here to read the abstract.


September 1, 2007 – Effects of Bilateral Subthalamic Nucleus Stimulation and Medication on Parkinsonian Speech Impairment

D’Alatri L, Paludetti G, Contarino MF, Galla S, Marchese MR, Bentivoglio AR. (2007) Effects of Bilateral Subthalamic Nucleus Stimulation and Medication on Parkinsonian Speech Impairment , Journal of Voice. Mar 15; [Epub ahead of print].Click here to read the abstract.


July 1, 2007 – Characteristics of Apathy in Parkinson’s Disease.

Kathy Dujardin, PhD, Pascal Sockeel, PhD, David Devos, MD, PhD, Marie Delliaux, PhD, Pierre Krystkowiak, MD, PhD, Alain Deste´e, MD, PhD, and Luc Defebvre, MD, PhD (2007). Characteristics of Apathy in Parkinson’s Disease. , Movement Disorders, Vol. 22, No. 6, 2007, pp. 778–784.Click here to read the abstract.


July 1, 2007 – Subthalamic nucleus deep brain stimulation in elderly patients–analysis of outcome and complications

Vesper, J., Haak, S., Ostertag, C., & Nikkhah, G. (2007). Subthalamic nucleus deep brain stimulation in elderly patients–analysis of outcome and complications , BMC Neurology. Mar 16; 7: 7.Click here to read the abstract.


May 1, 2007 – DBS-STN appropriate to treat severe Parkinson disease in an elderly population?

Derost PP, Ouchchane L, Morand D, Ulla M, Llorca PM, Barget M, Debilly B, Lemaire JJ, Durif F. DBS-STN appropriate to treat severe Parkinson disease in an elderly population? , Neurology, 68(17):1345-55IsClick here to read the abstract.


May 1, 2007 – Lower Urinary Tract Symptoms and Bladder Control in Advanced Parkinson’s Disease: Effects of Deep Brain Stimulation in the Subthalamic Nucleus.

Winge, K., Kroyer Nielsen, K., Stimple, H., Lokkegaard, A., Jensen, S. and Werdelin, L Lower Urinary Tract Symptoms and Bladder Control in Advanced Parkinson’s Disease: Effects of Deep Brain Stimulation in the Subthalamic Nucleus. , Movement Disorders 2007, 22(2), 220-225.Click here to read the abstract.


May 1, 2007 – NonMotor Symptoms

Friedman JH, Brown RG, Comella C, Garber CE, Krupp LB, Lou JS, Marsh L, Nail L, Shulman L, Taylor CB; Working Group on Fatigue in Parkinson’s Disease. (2007). Fatigue in Parkinson’s disease: a review. Movement Disorders. 2007 Feb 15;22(3):297-308 NonMotor Symptoms , Click here to read the abstract.


April 1, 2007 – Bilateral deep brain stimulation of the pedunculopontine and subthalamic nuclei in severe Parkinson’s disease

Stefani, A., Lozano, AM., Peppe, A., Stanzione, P., Galati, S., Tropepi, D., Pierantozzi, M., Brusa, L., Scarnati, E., & Mazzone, P. Bilateral deep brain stimulation of the pedunculopontine and subthalamic nuclei in severe Parkinson’s disease , Brain, 2007 Jan 24; [Epub ahead of print]Click here to read the abstract.


January 1, 2007 – A Randomized Trial of Deep-Brain Stimulation for Parkinson’s Disease.

Deuschl, G.,Schade-Brittinger C, Krack P, Volkmann J, Schafer H, Botzel K, Daniels C, Deutschlander A, Dillmann U, Eisner W, Gruber D, Hamel W, Herzog J, Hilker R, Klebe S, Kloss M, Koy J, Krause M, Kupsch A, Lorenz D, Lorenzl S, Mehdorn HM, Moringlane JR, Oertel W, Pinsker MO, Reichmann H, Reuss A, Schneider GH, Schnitzler A, Steude U, Sturm V, Timmermann L, Tronnier V, Trottenberg T, Wojtecki L, Wolf E, Poewe W, & Voges J (2006) A Randomized Trial of Deep-Brain Stimulation for Parkinson’s Disease. , 355, 9, 896-908Click here to read the abstract.


November 1, 2006 – A Randomized Trial of Deep-Brain Stimulation for Parkinson’s Disease

Deuschl, G.,Schade-Brittinger C, Krack P, Volkmann J, Schafer H, Botzel K, Daniels C, Deutschlander A, Dillmann U, Eisner W, Gruber D, Hamel W, Herzog J, Hilker R, Klebe S, Kloss M, Koy J, Krause M, Kupsch A, Lorenz D, Lorenzl S, Mehdorn HM, Moringlane JR A Randomized Trial of Deep-Brain Stimulation for Parkinson’s Disease , 355, 9, 896-908Click here to read the abstract.


September 1, 2006 – Subthalamic nucleus stimulation: improvements in outcome with reprogramming

Moro, Poon, Lozano, Saint-Cyr, & Lang Subthalamic nucleus stimulation: improvements in outcome with reprogramming , Arch Neurol. 2006 Jul 10; Epub ahead of printNote from the reviewers at The Parkinson Alliance: The following Current Science Review was made intentionally lengthy as it is our opinion that the area of DBS programming is a vital challenge to the PD community and this article expressly addresses these concerns. We hope that you read it with as much interest as we did.Click here to read the abstract.


July 1, 2006 – Stimulation of the subthalamic nucleus in Parkinson’s disease: a 5 year follow up

Schupbach, W. et al Stimulation of the subthalamic nucleus in Parkinson’s disease: a 5 year follow up , 2005 Dec;76(12):1640-4This article discusses the results of 37 patients with PD that underwent bilateral DBS-STN at a clinic in France. Patients were evaluated at 1 month prior to surgery and 6, 24, and 60 months after surgery. They had strict criteria for inclusion of patients for surgery and had attrition of 6 patients by the end of the study (5 deaths, 1 relocated). They found that the patients had more motor improvement with stimulation and levodopa combined versus either treatment alone. They also found less dyskinesias and less need for levodopa, but that the benefit decreased across time. Patients also had improvement in their activities of daily living at the 6 month point, which was lost at the later testing times. Scores on depression and cognitive screening remained the same across testing through 24 months, but performance on a cognitive screening measure began to worsen at the 60 month evaluation. Their patients did not experience permanent adverse events during the 5 year trial but had various transient events (e.g. emotional fluctuations, urinary retention, eyelid opening difficulties, weight gain). A total of 13 stimulators had to be replaced in the group of patients due to low power (anticipated or experienced) in the battery. The authors listed multiple side effects of intermittent stimulation due to the battery. One of the limitations of this article was that there was no control group of patients with PD to compare to those who underwent DBS-STN. The authors suggest that regardless of a control group there was sustained improvement five years after DBS-STN. They also suggested the possibility of neuroprotective factors of DBS-STN but noted the literature is mixed and mostly completed on animal models. They concluded by suggesting more long term studies to measure the efficacy and possible protective factors of DBS-STN.Click here to read the abstract.


July 1, 2006 – Deep-brain stimulation in Parkinson’s disease: long-term efficacy and safety – What happened this year

Benabid AL, Chabardes S, Seigneuret E Deep-brain stimulation in Parkinson’s disease: long-term efficacy and safety – What happened this year , 2005 Dec; 18(6):623-30Click here to read the abstract.


April 1, 2006 – Anesthesia for functional neurosurgery: review of complications

Journal of Neurosurgical AnesthesiologyVenkatraghavan, L., Manninen P, Mak P, Lukitto K, Hodaie M, Lozano A. (2006) Anesthesia for functional neurosurgery: review of complications Journal of Neurosurgical Anesthesiology, Jan;18(1):64-7The purpose of this study was to evaluate anesthesia difficulties that may occur during functional neurosurgery, such as in DBS. They found that 16% of their patients had intraoperative complications, including seizures (most common), severe headache, vomiting, shortness of breath, hypertension, and drowsiness. A small number of their patients experienced neurological changes, including speech difficulties, fluctuating level of consciousness (later found to have a small bleed at site of electrode), and one experienced a large bleed in the brain (this pt had a poor outcome). After surgery complications included, intracranial bleed (n=4), confusion (2), seizure (1), neurological deficit (3), and a cerebrospinal fluid leak (1). They concluded that their anesthesia method was successful in all but two of the patients and that most of their patients did not require sedation during their procedure. They highly suggested early awareness and monitoring of patient’s breathing, blood pressure, and fluid management by the anesthesiologist during surgery to avoid intra and postoperative complications. They indicated that the anesthesiologist should treat any difficulties early to avoid additional complications. They also noted the importance of a multidisciplinary treatment team to make sure that patient’s are correctly selected for this procedure to minimize any complications. Click here to read the abstract.


April 1, 2006 – Independent patterns of damage within magno-, parvo- and koniocellular pathways in Parkinson’s disease

Annals of NeurologySilva M.F., Faria P., Regateiro F.S., Forjaz V., Januario C., Freire A., Castelo-Branco M. (2005) Independent patterns of damage within magno-, parvo- and koniocellular pathways in Parkinson’s disease Annals of Neurology, Brain. Oct;128(Pt 10):2260-71This was a very detailed article discussing the literature for visual disturbances in patients with PD as well as a study looking at different patterns of visual dysfunction. They began by discussing that there are many ways to measure vision, which contributes to the variability of results amongst studies in the literature. These authors looked at various parts of the eye, down to different cellular levels to determine if vision difficulties in patients with PD were due to age or to the disease itself. The authors found that patients with PD had deficits in all areas of the visual pathway they measured. Disease duration and age were not found to fully explain these findings. They also found that visual dysfunction was related to severity and duration of PD, suggesting deterioration with disease progression as well age. They discussed the various biological causes for vision difficulties due to PD as well as aging.Click here to read the abstract.


April 1, 2006 – Falls in outpatients with Parkinson’s disease: frequency, impact and identifying factors

Journal of NeurosurgeryBalash, Y., Peretz C., Leibovich G., Herman T., Hausdorff J.M., Giladi N. (2005) Falls in outpatients with Parkinson’s disease: frequency, impact and identifying factors Journal of Neurosurgery, 2005 Nov; 252(11):1310-5These researchers wanted to look at frequency of falls and associated factors in patients with PD. They briefly reviewed why studying falls, a gait difficulty with serious complications (physical injury, fears, restriction of activities, and admission to nursing homes) for the patient with PD, is important. They reported approximately 1/3-2/3 of patients with PD experience falls but that associated factors are not as well documented or understood. The authors also looked at cognitive function, depression, general health, activities of daily living, balance, gait, and bladder dysfunction. About a third of the patients in their study had difficulties with falls. The authors also found that urinary incontinence and duration of PD were the only predictors of falling. Additionally, they found that patients prone to falling had worse motor difficulties, depressive symptoms, lower activities of daily living, and identified their health as poorer. Additional they found that if a patient had PD and urinary incontinence, he/she was 6 times more likely to have repeated falls. The authors discussed a limitation to their study including that it was retrospective (asking patients and carers to remember how many falls occurred over the last year may be difficult and inaccurate), which may have lowered the actual number of falls that individuals had. The authors suggested that the actual number of falls in their group may be higher than that reported due to multiple factors. They also encouraged medical professionals and family members to be aware that if a patient with PD has incontinence that they are more likely to have difficulties with falls and may require more fall precautions or associated therapies.Click here to read the abstract.


January 1, 2006 – Bilateral deep brain stimulation of the pedunculopontine nucleus for Parkinson’s disease

Plaha, P. & Gill, S. (2005) Bilateral deep brain stimulation of the pedunculopontine nucleus for Parkinson’s disease , Neuroreport. Nov 28; 16(17):1883-7The purpose of this article was to look at stimulation of the pedunculopontine nucleus (PPN) in 2 patients with PD, specifically for better control of gait and postural instability. They found that both patients had improvement in gait, postural instability, and other motor features of PD in both the on and off medication states. The authors noted there were no medical or cognitive complications for either patient. They also discussed the stimulation parameters and found in both patients that lower frequencies worked better than higher frequencies. It should be noted that there was a relatively short follow-up time of these patients and that they should be followed long term to fully evaluate improvement in motor functions as well as other possible long term effects.Click here to read the abstract.


January 1, 2006 – Visualizing the next steps in Parkinson’s disease

Bodis-Wollner I.(2002) Visualizing the next steps in Parkinson’s disease , Aug;59(8):1233-4Click here to read the abstract.


January 1, 2006 – Progressive worsening of spatial and chromatic processing deficits in Parkinson’s disease

Diederich NJ, Raman R, Leurgans S, Goetz CG. (2002). Progressive worsening of spatial and chromatic processing deficits in Parkinson’s disease , Aug;59(8):1249-52Click here to read the abstract.


November 1, 2005 – A disease-specific psychosocial questionnaire for Parkinson’s disease caregivers

Journal of NeurologySpliethoff-Kamminga NG, Zwinderman AH, Springer MP, Roos RA A disease-specific psychosocial questionnaire for Parkinson’s disease caregivers Journal of Neurology, Oct; 250(10):1162-8Click here to read the abstract.


November 1, 2005 – Multidisciplinary rehabilitation for people with Parkinson’s disease: a randomized controlled study

Journal of Neurology, Neurosurgery, and PsychiatryWade DT, Gage H, Owen C, Trend P, Grossmith C, Kaye J Multidisciplinary rehabilitation for people with Parkinson’s disease: a randomized controlled study Journal of Neurology, Neurosurgery, and Psychiatry, 2003 Feb; 74(2):158-62Click here to read the abstract.


November 1, 2005 – Cognitive behavioral therapy (CBT) for carers of patients with Parkinson’s disease: A preliminary randomized controlled trial

Secker, D. & Brown, R. (2005) Cognitive behavioral therapy (CBT) for carers of patients with Parkinson’s disease: A preliminary randomized controlled trial , 76, 491-497Click here to read the abstract.


November 1, 2005 – Mental symptoms in Parkinson’s disease are important contributors to caregiver distress

Aarsland, Larsen, Karlsen, Lim & Tandberg. (1999) Mental symptoms in Parkinson’s disease are important contributors to caregiver distress , 14, 866-874Click here to read the abstract.


November 1, 2005 – Diagnosis and initial management of Parkinson’s disease

Nutt, J. & Wooten, G. (2005) Diagnosis and initial management of Parkinson’s disease , 353, 1021-1027Click here to read the abstract.


November 1, 2005 – Functional surgery for Parkinson’s disease treatment: A structured analysis of a decade of published literature

Boucai, L., Cerquetti, D., & Merello, M. (2004) Functional surgery for Parkinson’s disease treatment: A structured analysis of a decade of published literature , 18, 213-222Click here to read the abstract.


September 1, 2005 – Does type of disease matter? Gender differences among Alzheimer’s and Parkinson’s disease spouse caregivers

Hooker, Manoogian-O’Dell, Monahan, Frazier, and Shifren (2000) Does type of disease matter? Gender differences among Alzheimer’s and Parkinson’s disease spouse caregivers , Oct;40(5):568-73Click here to read the abstract.


September 1, 2005 – Falling in Parkinson’s disease: The impact on informal caregivers

Davey, Wiles, Ashburn, & Murphy (2004) Falling in Parkinson’s disease: The impact on informal caregivers , 2004 Dec 2;26(23):1360-6Click here to read the abstract.


September 1, 2005 – The comparative effects of medical therapies for Parkinson’s Disease

Horn, S. & Stern, MB (2004) The comparative effects of medical therapies for Parkinson’s Disease , 2004 Oct 12;63(7 Suppl 2):S7-12Click here to read the abstract.


September 1, 2005 – Bilateral subthalamic nucleus deep brain stimulation in a patient with cervical dystonia and essential tremor

Movement DisordersChou KL, Hurtig HI, Jaggi JL, Baltuch GH. (2005) Bilateral subthalamic nucleus deep brain stimulation in a patient with cervical dystonia and essential tremor Movement Disorders, 2005 Mar;20(3):377-80Click here to read the abstract.


September 1, 2005 – Rationale for current therapies in Parkinson’s disease

Rommrell, Fernandez, & Okun Rationale for current therapies in Parkinson’s disease , 2003 Oct;4(10):1747-61Click here to read the abstract.


July 1, 2005 – Deep brain stimulation for movement disorders: morbidity and mortality in 109 patients

Journal of NeurosurgeryUmemura A, Jaggi JL, Hurtig HI, Siderowf AD, Colcher A, Stern MB, Baltuch GH Deep brain stimulation for movement disorders: morbidity and mortality in 109 patients Journal of Neurosurgery, 2003 Apr;98(4):779-84Click here to read the abstract.


July 1, 2005 – Adverse effects of subthamalmic nucleus DBS in a patient with multiple system atrophy

NeurologyTarsy D, Apetauerova D, Ryan P, Norregaard T Adverse effects of subthamalmic nucleus DBS in a patient with multiple system atrophy Neurology, 2003 Jul 22;61(2):247-9Click here to read the abstract.


July 1, 2005 – Subthamalmic nucleus vs. globus pallidus interna deep brain stimulation, the rematch: will pallidal deep brain stimulation make a triumphant return

Archives of NeurologyOkun MS, Foote KD Subthamalmic nucleus vs. globus pallidus interna deep brain stimulation, the rematch: will pallidal deep brain stimulation make a triumphant return Archives of Neurology, 2005 Apr;62(4):554-60Click here to read the abstract.


July 1, 2005 – Pallidal vs subthalamic nucleus deep brain stimulation in Parkinson’s disease

Anderson VC, Burchiel KJ, Hogarth P, Favre J, Hammerstad JP Pallidal vs subthalamic nucleus deep brain stimulation in Parkinson’s disease , 2005 Apr;62(4):554-60Click here to read the abstract.


July 1, 2005 – Most effective stimulation site in subthalamic deep brain stimulation for Parkinson’s disease

Movement DisordersHerzog J, Fietzek U, Hamel W, Morsnowski A, Steigerwald F, Schrader B, Weinert D, Pfister G, Muller D, Mehdorn HM, Deuschl G, Volkmann J Most effective stimulation site in subthalamic deep brain stimulation for Parkinson’s disease Movement Disorders, 2004 Sep;19(9):1050-4Click here to read the abstract.


July 1, 2005 – Management of Referred Deep Brain Stimulation Failures: A Retrospective Analysis From 2 Movement Disorders Centers

Archives of NeurologyOkun MS, Tagliati M, Pourfar M, Fernandez HH, Rodriguez RL, Alterman RL, Foote KD Management of Referred Deep Brain Stimulation Failures: A Retrospective Analysis From 2 Movement Disorders Centers Archives of Neurology, 2005 Jun 13; Epub ahead of printClick here to read the abstract.


May 1, 2005 – Pathological gambling associated with dopamine agonist therapy in Parkinson’s disease

NeurologyDriver-Dunckley, E., Samanta, J., Stacy, M Pathological gambling associated with dopamine agonist therapy in Parkinson’s disease Neurology, 2003 Aug 12;61(3):422-3Click here to read the abstract.


May 1, 2005 – Pathologic gambling in patients with Parkinson’s disease

Clinical NeuropharmacologyGschwandtner, U, Aston J, Renaud S, & Fuhr P Pathologic gambling in patients with Parkinson’s disease Clinical Neuropharmacology, 2001 May-Jun;24(3):170-2Click here to read the abstract.


May 1, 2005 – Testosterone deficiency and apathy in Parkinson’s disease: a pilot study

Journal of Neurology, Neurosurgery, and PsychiatryReady, R., Friedman, J., Grace, J., & Fernandez, H. (2004) Testosterone deficiency and apathy in Parkinson’s disease: a pilot study Journal of Neurology, Neurosurgery, and Psychiatry, 75, 1323-1326Click here to read the abstract.


April 1, 2005 – The impact of comorbid disease and injuries on resource use and expenditures in parkinsonism

NeurologyBloem BR, Munneke M, Carpenter MG, Allum JH. (2003) The impact of comorbid disease and injuries on resource use and expenditures in parkinsonism Neurology, Oct 14;61(7):1023; author reply 1023-4Click here to read the abstract.


April 1, 2005 – A response to the Pressley article to address fewer arm fractures in patients with PD

NeurologyBloem BR, Munneke M, Carpenter MG, Allum JH. (2003) A response to the Pressley article to address fewer arm fractures in patients with PD Neurology, Oct 14;61(7):1023; author reply 1023-4Click here to read the abstract.


April 1, 2005 – Effects of stereotactic neurosurgery on postural instability and gait in Parkinson’s disease

Movement DisordersBakker M, Esselink RA, Munneke M, Limousin-Dowsey P, Speelman HD, Bloem BR. (2004) Effects of stereotactic neurosurgery on postural instability and gait in Parkinson’s disease Movement Disorders, Sep;19(9):1092-9Click here to read the abstract.


April 1, 2005 – Sweating dysfunction in Parkinson’s disease

Movement DisordersSwinn L, Schrag A, Viswanathan R, Bloem BR, Lees A, Quinn N. (2003) Sweating dysfunction in Parkinson’s disease Movement Disorders, Dec;18(12):1459-63Click here to read the abstract.


April 1, 2005 – Effects of subthalamic nucleus stimulation on urodynamic findings in patients with Parkinson’s disease

Journal of NeurologyFinazzi-Agro, E., A. Peppe, et al. (2003) Effects of subthalamic nucleus stimulation on urodynamic findings in patients with Parkinson’s disease Journal of Neurology, 169(4): 1388-91Click here to read the abstract.


April 1, 2005 – Short-term effect of a single levodopa dose on micturition disturbance in Parkinson’s disease patients with the wearing-off phenomenon

Movement DisordersUchiyama, T., R. Sakakibara, et al. (2003) Short-term effect of a single levodopa dose on micturition disturbance in Parkinson’s disease patients with the wearing-off phenomenon Movement Disorders, 18(5): 573-8Click here to read the abstract.


April 1, 2005 – Effect of subthalamic deep brain stimulation on the function of the urinary bladder

Annals of NeurologySeif, C., J. Herzog, et al. (2004) Effect of subthalamic deep brain stimulation on the function of the urinary bladder Annals of Neurology, 55(1): 118-20Click here to read the abstract.


April 1, 2005 – Swallowing abnormalities and dyskinesia in Parkinson’s disease

Annals of NeurologyMonte, F. S., F. P. da Silva-Junior, et al. (2004) Swallowing abnormalities and dyskinesia in Parkinson’s disease Annals of Neurology, Epub ahead of printClick here to read the abstract.


April 1, 2005 – Assessing comorbidity in patients with Parkinson’s disease

Movement DisordersVisser, M., J. Marinus, et al (2004) Assessing comorbidity in patients with Parkinson’s disease Movement Disorders, 19(7): 824-8Click here to read the abstract.


January 1, 2005 – Caffeine, postmenopausal estrogen, and risk of Parkinson’s disease

Ascherio, A.. Chen H, Schwarzschild MA, Zhang SM, Colditz GA, Speizer FE. (2003) Caffeine, postmenopausal estrogen, and risk of Parkinson’s disease , 2003 Mar 11;60(5):790-5Click here to read the abstract.


January 1, 2005 – Plasma testosterone levels in Alzheimer and Parkinson’s diseases

Okun, M., DeLong, M, Hanfelt, J., Gearing, M., & Levey, A.. (2004 Plasma testosterone levels in Alzheimer and Parkinson’s diseases , 2004 Feb 10;62(3):411-3Click here to read the abstract.


January 1, 2005 – Beneficial effects of testosterone replacement for the nonmotor symptoms of Parkinson’s disease

Okun, M., Walter, B., McDonald, W., Tenover, J., Green, J., Juncos, J., & DeLong, M. (2002, Nov.) Beneficial effects of testosterone replacement for the nonmotor symptoms of Parkinson’s disease , 59, 1750-1753Click here to read the abstract.


January 1, 2005 – Refractory nonmotor symptoms in male patients with Parkinson’s disease due to testosterone deficiency: A common unrecognized comorbidity

Okun, M., McDonald, W., & DeLong, M. (2002, May) Refractory nonmotor symptoms in male patients with Parkinson’s disease due to testosterone deficiency: A common unrecognized comorbidity , 59, 807-811Click here to read the abstract.


January 1, 2005 – Parkinson’s disease with old-age onset: a comparative study with subjects with middle-age onset

Diederich NJ, Moore CG, Leurgans SE, Chmura TA, Goetz CG. (2003) Parkinson’s disease with old-age onset: a comparative study with subjects with middle-age onset , Apr;60(4):529-33Click here to read the abstract.


January 1, 2005 – Role of sensory input and muscle strength in maintenance of balance, gait, and posture in Parkinson’s disease: a pilot study

Nallegowda M, Singh U, Handa G, Khanna M, Wadhwa S, Yadav SL, Kumar G, & Behari M. (2004 Dec) Role of sensory input and muscle strength in maintenance of balance, gait, and posture in Parkinson’s disease: a pilot study , 83(12):898-908Click here to read the abstract.


January 1, 2005 – Falls and freezing of gait in Parkinson’s disease: a review of two interconnected, episodic phenomena

Bloem BR, Hausdorff JM, Visser JE, Giladi N. (2004 Aug) Falls and freezing of gait in Parkinson’s disease: a review of two interconnected, episodic phenomena , 19(8):871-84Click here to read the abstract.


January 1, 2005 – Colonic transit time and rectoanal videomanometry in Parkinson’s disease

Sakakibara, R., T. Odaka, et al. (2003) Colonic transit time and rectoanal videomanometry in Parkinson’s disease , 74(2): 268-72Click here to read the abstract.


January 1, 2005 – Implantation of bilateral deep brain stimulators in patients with Parkinson’s disease and preexisting cardiac pacemakers

Senatus, P. B., S. McClelland, 3rd, et al. (2004) Implantation of bilateral deep brain stimulators in patients with Parkinson’s disease and preexisting cardiac pacemakers , 101(6): 1073-7Click here to read the abstract.


January 1, 2005 – Psychiatric comorbidities in patients with Parkinson’s disease and psychosis

Marsh, L., J. R. Williams, et al (2004) Psychiatric comorbidities in patients with Parkinson’s disease and psychosis , 63(2): 293-300Click here to read the abstract.


January 1, 2005 – Deep brain stimulation for Parkinson’s disease dissociates mood and motor circuits: a functional MRI case study

Movement DisordersStefurak T, Mikulis D, Mayberg H, Lang AE, Hevenor S, Pahapill P, Saint-Cyr J, & Lozano A Deep brain stimulation for Parkinson’s disease dissociates mood and motor circuits: a functional MRI case study Movement Disorders, 2003 Dec;18(12):1508-16.Click here to read the abstract.


January 1, 2005 – Duodenal levodopa infusion monotherapy vs oral polypharmacy in advanced Parkinson’s disease

Nyholm D, Nilsson Remahl AI, Dizdar N, Constantinescu R, Holmberg B, Jansson R, Aquilonius SM, & Askmark H Duodenal levodopa infusion monotherapy vs oral polypharmacy in advanced Parkinson’s disease , 2005 Jan 25;64(2):216-23Click here to read the abstract.


January 1, 2005 – Parkinson’s Disease and Anxiety

Walsh, K. & Bennett, G. (2001) Parkinson’s Disease and Anxiety , 77, 88-93Click here to read the abstract.


January 1, 2005 – Expectation modulates the response to subthalamic nucleus stimulation in Parkinsonian patients

NeuroReportPollo, A., Torre, E., Lopiano, L., Rizzone, M., Lanotte, M., Cavanna, A., Bergamasco, B., & Benedetti, F. (2002) Expectation modulates the response to subthalamic nucleus stimulation in Parkinsonian patients NeuroReport, 13, 1383-1386Click here to read the abstract.


May 1, 2004 – Improvement of voicing in patients with Parkinson’s disease by speech therapy

Neurologyde Swart, Bert J. M; Willemse, S. C; Maassen, B. A. M; Horstink, M. W. I. M. (2003) Improvement of voicing in patients with Parkinson’s disease by speech therapy Neurology, 60(3), 498-500.Click here to read the abstract.


May 1, 2004 – Intensive voice treatment (LSVT) for patients with Parkinson’s disease: a 2 year follow up

Journal of Neurology, Neurosurgery, and PsychiatryRamig L.O., Sapir S., Countryman S., Pawlas A.A., O’Brien C., Hoehn M., & Thompson L.L. (2001) Intensive voice treatment (LSVT) for patients with Parkinson’s disease: a 2 year follow up Journal of Neurology, Neurosurgery, and Psychiatry, 71(4), 493-8Click here to read the abstract.


May 1, 2004 – Effect of stimulation of the subthalamic nucleus on oral control of patients with parkinsonism

Journal of Neurology, Neurosurgery, and PsychiatryGentil, M., Garcia-Ruiz, P., Pollak, P., & Benabid, A. (1999) Effect of stimulation of the subthalamic nucleus on oral control of patients with parkinsonism Journal of Neurology, Neurosurgery, and Psychiatry, 67, 329-333Click here to read the abstract.


May 1, 2004 – Axial parkinsonian symptoms can be improved: the role of levodopa and bilateral subthalamic stimulation

Journal of Neurology, Neurosurgery, and PsychiatryBejjani, B.P., Gervais, D., Arnulf, I., Papadopoulos, S., Demeret, S., Bonnet, A.M., Cornu, P., Damier, P., Agid, Y. (2000) Axial parkinsonian symptoms can be improved: the role of levodopa and bilateral subthalamic stimulation Journal of Neurology, Neurosurgery, and Psychiatry, 68, 595-600Click here to read the abstract.


May 1, 2004 – Voice and speech abnormalities in Parkinson disease: Relation to severity of motor impairment, duration of disease, medication, depression, gender, and age

Journal of Medical Speech-Language PathologySapir, S., Pawlas, A.A., Ramig, L.O., Countryman, S., O’Brien, C., Hoehn, M.M., & Thompson, L.A. (2001) Voice and speech abnormalities in Parkinson disease: Relation to severity of motor impairment, duration of disease, medication, depression, gender, and age Journal of Medical Speech-Language Pathology, 9(4), 213-226Click here to read the abstract.


May 1, 2004 – Parkinsonian speech disfluencies: Effects of L-dopa-related fluctuations

Journal of Fluency DisordersGoberman, A.M. & Blomgren, M. (2003) Parkinsonian speech disfluencies: Effects of L-dopa-related fluctuations Journal of Fluency Disorders, 28(1), 55-70Click here to read the abstract.


May 1, 2004 – Effects of speech therapy and pharmacologic and surgical treatments on voice and speech in Parkinson’s disease: A review of the literature

Journal of Communication DisordersSchulz, G.M. & Grant, M.K. (2000) Effects of speech therapy and pharmacologic and surgical treatments on voice and speech in Parkinson’s disease: A review of the literature Journal of Communication Disorders, 33(1), 59-88Click here to read the abstract.


May 1, 2004 – Speech initiation hesitation’ following subthalamic nucleus stimulation in a patient with Parkinson’s disease

European NeurologyMoretti, R., Torre, P., Antonello, R. M., Capus, L., Gioulis, M., Marsala, S. Zambito, Cazzato, G., & Bava, A. (2003) Speech initiation hesitation’ following subthalamic nucleus stimulation in a patient with Parkinson’s disease European Neurology, 49(4), 251-253Click here to read the abstract.


January 1, 2004 – Surgical treatment of Parkinson’s disease

Koller WC., Pahwa R., Lyons KE., & Albanese A. (1999) Surgical treatment of Parkinson’s disease , 167(1),1-10Click here to read the abstract.


January 1, 2004 – Surgical treatment of Parkinson’s disease

Obeso J.A., Rodriguez M.C., Gorospe A., Guridi J., Alvarez L., & Macias R. (1997) Surgical treatment of Parkinson’s disease , 6(1):125-45Click here to read the abstract.


January 1, 2004 – Five-year follow-up of bilateral stimulation of the subthalamic nucleus in advanced ParkinsonÕs disease

Krack, P., Batir, A., Van Blercom, N., Chabardes, S., Fraix, V., Ardouin, C., Koudsie, A., Limousin, P., Benazzouz, A., LeBas, J., Benabid, A., & Pollak, P. (2003) Five-year follow-up of bilateral stimulation of the subthalamic nucleus in advanced ParkinsonÕs disease , 349 (20), 1925-1934Click here to read the abstract.


January 1, 2004 – Hypophonia in Parkinson’s disease: Neural correlates of voice treatment revealed by PET

Liotti, M., Ramig, L. O., Vogel, D., New, P., Cook, C. I., Ingham, R. J., Ingham, J. C., & Fox, P. T. (2003) Hypophonia in Parkinson’s disease: Neural correlates of voice treatment revealed by PET , Vol 60(3), 432-440Click here to read the abstract.


January 1, 2004 – An investigation of the effects of subthalamic nucleus stimulation on acoustic measures of voice

Dromey, C., Kumar, R., Lang, A., & Lozano, A. (2000) An investigation of the effects of subthalamic nucleus stimulation on acoustic measures of voice , 15 (6), 1132-1138Click here to read the abstract.


January 1, 2004 – Bilateral subthalamic stimulation effects on oral force control in Parkinson’s disease

Pinto, S., Gentil, M., Fraix, V., Benabid, A.L., & Pollak, P. (2003) Bilateral subthalamic stimulation effects on oral force control in Parkinson’s disease , 250, 179-187Click here to read the abstract.


January 1, 2004 – Chronic inhibition of the subthalamic nucleus in Parkinson’s disease

Krause, M., Fogel, W., Mayer, P., Kloss, M., & Tronnier, V. (2004) Chronic inhibition of the subthalamic nucleus in Parkinson’s disease , 219, 119-124Click here to read the abstract.


January 1, 2004 – Processing emotional tone from speech in Parkinson’s disease: A role for the basal ganglia

Pell, M.D. & Leonard, C.L. (2003) Processing emotional tone from speech in Parkinson’s disease: A role for the basal ganglia , 3(4), 275-288Click here to read the abstract.


January 1, 2004 – Lateralized effects of subthalamic nucleus stimulation on different aspects of speech in Parkinson’s disease

Santens, P., De Letter, M., Van Borsel, J., De Reuck, J., Caemaert, J. (2003) Lateralized effects of subthalamic nucleus stimulation on different aspects of speech in Parkinson’s disease , 87(2), 253-258Click here to read the abstract.


January 1, 2004 – Effect of bilateral stimulation of the subthalamic nucleus on parkinsonian dysarthria

Gentil, M., Pinto, S., Pollack, P., & Benabid, A. (2003) Effect of bilateral stimulation of the subthalamic nucleus on parkinsonian dysarthria , Vol 85(2), 190-196Click here to read the abstract.


January 1, 2004 – Effect of bilateral stimulation of the subthalamic nucleus in parkinsonian voice

Gentil, M., Chauvin, P., Pinto, S., Pollak, P., & Benabid, A.L . (2001) Effect of bilateral stimulation of the subthalamic nucleus in parkinsonian voice , 78, 233-240Click here to read the abstract.


January 1, 2004 – Depression in Parkinson’s disease: Impediments to recognition and treatment options

Poewe, W., & Luginger, E, (1999) Depression in Parkinson’s disease: Impediments to recognition and treatment options , 52 (7 Suppl 3): S2-S6Click here to read the abstract.


January 1, 2004 – Effect on mood of subthalamic DBS for Parkinson’s disease: A consecutive series of 24 patients

Berney, A., Vingerhoets, F., Perrin, A., Guex, P., Villemure, J-G, Burkard, P.R., Benkelfat, C., & Ghika, J. (2002 Effect on mood of subthalamic DBS for Parkinson’s disease: A consecutive series of 24 patients , 59, 1427-1429Click here to read the abstract.


January 1, 2004 – Depression leading to attempted suicide after bilateral subthalamic nucleus stimulation for Parkinson’s disease

Doshi, P.K., Chhaya, N., & Bhatt, M.H. (2002) Depression leading to attempted suicide after bilateral subthalamic nucleus stimulation for Parkinson’s disease , 17, 1084-1085Click here to read the abstract.


January 1, 2004 – Behavioral disorders, Parkinson’s disease and subthalamic stimulation

Houeto, J. L., Mesnage, V., Mallett, L., (2002) Behavioral disorders, Parkinson’s disease and subthalamic stimulation , 72, 701-707Click here to read the abstract.


January 1, 2004 – Cognitive and behavioural effects of chronic stimulation of the subthalamic nucleus in patients with Parkinson’s disease

Daniele, A., Albanese, A., Contarino, M.F., Zinzi, P., Barbier, A., Gasparini, F., Romito, L.M.A., Bentivoglio, A.R., & Scerrati, M. (2003) Cognitive and behavioural effects of chronic stimulation of the subthalamic nucleus in patients with Parkinson’s disease , 74, 175-182Click here to read the abstract.


January 1, 2004 – Subthalamic nucleus stimulation in Parkinson’s disease: Clinical evaluation of 18 patients

Thobois, S., Mertens, P., Guenot, M., Hermier, M., Mollion, H., Bouvard, M., Chazot, G., Broussolle, E., Sindou, M. (2002) Subthalamic nucleus stimulation in Parkinson’s disease: Clinical evaluation of 18 patients , 249, 529-524Click here to read the abstract.


January 1, 2004 – Emotional changes in multiple sclerosis and Parkinson’s disease

Rao, S.M., Huber, S.J., & Bornstein, R.A. (1992) Emotional changes in multiple sclerosis and Parkinson’s disease , 60 (3), 369-378Click here to read the abstract.


January 1, 2004 – Depression and Parkinson’s disease: A new look at an old problem

Edwards, E., Kitt, C., Oliver, E., Finkelstein, J., Wagster, M., & McDonald, W. (2002) Depression and Parkinson’s disease: A new look at an old problem , 16, 39-48Click here to read the abstract.


January 1, 2004 – Depression in Parkinson’s disease

Brooks, D. & Doder, M. (2001) Depression in Parkinson’s disease , 14 (4), 465-470Click here to read the abstract.


January 1, 2004 – Neuropsychological functioning following bilateral subthalamic nucleus stimulation in Parkinson’s disease

Morrison, C.E., Borod, J.C., Perrine, K., Beric, A., Brin, M.F., Rezai, A., Kelly, P., Sterio, D., Germano, I., Weisz, D., & Olanow, C.W. (2003) Neuropsychological functioning following bilateral subthalamic nucleus stimulation in Parkinson’s disease , 41274Click here to read the abstract.


January 1, 2004 – Bilateral subthalamic or pallidal stimulation for Parkinson’s disease affects neither memory nor executive functions: a consecutive series of 62 patients

Ardouin, C., Pillon, B., Peiffer, E., et al. (1999) Bilateral subthalamic or pallidal stimulation for Parkinson’s disease affects neither memory nor executive functions: a consecutive series of 62 patients , 46, 217-223.Click here to read the abstract.


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