Subthalamic nucleus stimulation in Parkinson’s disease: Clinical evaluation of 18 patients
Thobois, S., Mertens, P., Guenot, M., Hermier, M., Mollion, H., Bouvard, M., Chazot, G., Broussolle, E., Sindou, M. (2002) Subthalamic nucleus stimulation in Parkinson’s disease: Clinical evaluation of 18 patients , 249, 529-524
Eighteen consecutive severely affected PD patients were evaluated clinically before and 6 months after the DBS-STN. Additionally, a 12 months follow-up was available in 14 patients. This study confirms the great value of subthalamic nucleus stimulation in the treatment of intractable PD. However, some individuals experienced episodes of depression following surgical procedures. Consequently, some adverse events, including depression, may be taken into account in the inclusion criteria and also in the post-operative outcome.