Research Insights

Depression in Parkinson’s disease: Impediments to recognition and treatment options

Poewe, W., & Luginger, E, (1999) Depression in Parkinson’s disease: Impediments to recognition and treatment options , 52 (7 Suppl 3): S2-S6

These investigators provide a good review of the prevalence, recognition, and treatment options for depression in PD. They indicated that an independent abnormality rather than a maladaptive response to disease likely causes parkinsonian depression, in that the degree of depression is not correlated with PD severity. Prognostically, depressive features may represent a subtle premorbid state heralding the onset o PD or an accelerated cognitive decline thereafter. Therapeutic mainstays for parkinsonian depression are discussed.

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