Controlling Gait Coordination with STN-DBS Improves Freezing of Gait in Parkinson’s disease
Fasano, A., Herzog, J., Seifert, E., Stolze, H., Falk, D., Reese, R., Volkmann, J., Deuschl, G. (2011). Controlling Gait Coordination with STN-DBS Improves Freezing of Gait in Parkinson’s disease , Modulation of gait coordination by subthalamic stimulation improves freezing of gait. Movement Disorders, 26(6): 844-851.
A recent study conducted by researchers of the University of Kiel and the Deaconess Hospital in Germany, establishes that STN-DBS may provide an opportunity to improve FOG in PD by allowing doctors to adjust the symmetry and coordination of patient gait. According to the study, since FOG patients often display abnormal symmetry and coordination between each leg, these factors may impair the gait process and contribute to freezing in PD. However, by adjusting the voltage (electrical intensity) of stimulation in each side of the brain that controls the dysfunction in the respective leg, researchers suggest that STN-DBS may be able to alter gait symmetry and coordination and, thus, improve FOG in PD. This suggestion was based on a comparison of gait coordination and FOG frequency and duration in 13 patients with PD under four different stimulation conditions (i.e. voltage settings) of STN-DBS. Click here to download a PDF of this review.