Research Insights

Behavioral disorders, Parkinson’s disease and subthalamic stimulation

Houeto, J. L., Mesnage, V., Mallett, L., (2002) Behavioral disorders, Parkinson’s disease and subthalamic stimulation , 72, 701-707

Houeto and colleagues analyzed 24 parkinsonian patients who were successfully treated by bilateral STN stimulation for the presence of behavioral disorders. Improvement in parkinsonian motor disability is not necessarily accompanied by improvement in mood function and quality of life. Social adjustments were impaired in 15 patients. Behavioral and psychiatric changes that were seen in some of these patients included increased mood swings, aggressiveness, irritability, depressed mood, thoughts of suicide, social withdraw, and abnormal sexual behavior.

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