The Parkinson Alliance Blog

Archive for the ‘Research’ Category

Project Emma and Parkinson’s Disease

Tuesday, May 16th, 2017

Neurodegenerative Diseases, the Need for Research Dollars, and The Resilience Project

Tuesday, August 2nd, 2016

Neurographic
iBiology has an eye-opening video that we invite you to watch called, Neurodegenerative disease: The Coming Epidemic.  In it, Dr. Gregory Petsko discusses how our population is aging and how with that comes an increase in neurodegenerative diseases, such as Parkinson’s. He makes a clear case for the need for research dollars.  He also explains that while most neurodegenerative diseases “arises sporadically, about 10% has a direct genetic cause.”  It is the genetic cause and how researchers are studying it that is incredibly exciting.

He introduces us to Douglas Whitney of Port Orchard, Washington whom he calls “the most interesting man in the world.”  He tells us that about half of the Whitney family has died in their 40s or 50s because of a genetic mutation that causes Alzheimer’s disease.  Mr. Whitney has the mutated gene.  By all accounts, he too should have died from Alzheimer’s.  However, at age 67 he is still alive and shows no signs of the disease.  The question is why.  What can researchers learn from what else Doug Whitney may have in his genetic make-up?  You can watch the video below and find additional information, including more videos in the series and related articles, here .

After watching the video, you may find yourself wondering how many other Douglas Whitneys may be among us.  In April 2016, The New York Times reported in an article entitled, People Who Avoided Illness Could Be Key in Treating Those Who Didn’t that “researchers searched databases containing genetic sequences from nearly 600,000 healthy adults” and discovered 13 who may hold clues “to treating others who did not escape the gene’s effects.” The excitement of those 13 was very short lived because while the participants in the databases gave their DNA, they also signed an agreement that they would remain anonymous.  In short, it was back to square one.

This, however, sparked the idea for The Resilience Project which “aims to discover hidden factors that protect people from disease.” The Project is searching for people worldwide who, “according to medical textbooks, should be sick but have somehow escaped typical signs and symptoms of the disease.” For this project, anyone who agrees to have their DNA sequenced also agrees to be contacted by researchers if they have a mutated gene that should have made them ill but did not. This Project presents the opportunity to open the door to potentially life-save treatments! Currently you can sign up at The Resilience Project, and we encourage you to do so. With some luck, we may find a few genetic winners among us to help researchers pave the way to a cure.

Margaret Tuchman and her blogging partner Gloria Hansen